Dr Alwyn Mwinga
Topic: Reducing TB morbidity and mortality in high HIV prevalence settings – community approaches to strengthening the TB cascade.
Dr Alwyn Mwinga is a physician trained at the University of Zambia and the University of London. Following her postgraduate training at the London School of Hygiene and Tropical Medicine (LSHTM), she spent 10 years working in TB/HIV research. In recognition of her contributions to TB and HIV, she was awarded a Global Health Achievement award by the CDC’s Office of Global Health in 2007 and the PEPFAR Lifetime Achievement award by the US Office of the Global AIDS Coordinator in 2011. After 12 years working in public health, Dr. Mwinga returned to the field of research and is now Zambart’s Chief Executive Officer since May 2013. Zambart is a Zambian research NGO, whose research efforts focus primarily on HIV and TB in large scale community-based trials.
Dr Helen Macdonald
Department of Social Anthropology, UCT
Topic: TB and Stigma
Anthropologist Dr Helen Macdonald has focused on gaining a more nuanced understanding of the social and political implications of TB in India and South Africa. In 2016, she was awarded a Wellcome Trust Community Engagement Grant for her TB project entitled Swallowing the World. Her co-edited volume with Ian Harper, Understanding Tuberculosis and its Control: Anthropological and Ethnographic Approaches, is due to be released in 2018.
Dr Iqbal Master
Head of department, MDR TB unit, King Dinizulu Hospital, Durban.
Topic: Treating DR TB at the coalface: challenges and successes
As Head and Clinical Manager at the MDR TB Unit at King Dinuzulu Hospital and over 23 years of working with MDR/XDR patients, he has gained invaluable knowledge and experience in managing the complexities of his patients that he will share with conference delegates. He is a member of both the Provincial and National Drug Resistant TB Advisory Committee and is involved in multiple studies in Drug Resistant TB.
Dr Nazir Ismail
National Institute of Communicable Diseases (NICD)
Topic: Finding TB and DR-TB using current and next generation technologies
Dr Ismail is the Head of the Centre for Tuberculosis incorporating the WHO supranational TB Reference Laboratory at the National Institute of Communicable Diseases/NHLS. He is a pathologist by training and is the lead tuberculosis researcher at NICD with a focus on TB epidemiology, public health responses and transmission.
Mr David Mametja
Chief Director, National Department of Health TB Control Programme.
Topic: Will we win the battle? Finding the missing TB patients in SA.
Mr Lerole David Mametja is a public health specialist and has more than 20 years of experience in this field. He was Executive Director of the Health Systems Trust (HST), a NGO supporting public-private partnerships in health. He was also Regional Health Sector Manager for RTI International (linked to University of North Carolina), overseeing its health programme in the Southern African Development Community (SADC), particularly in Mozambique, Lesotho, Swaziland and Namibia. He served as CEO of the Health and Welfare Sector Education Training Authority (HWSETA), an entity that focuses on providing training and skills development opportunities for South Africans. He holds a Masters degree in Public Health (MPH) (Health Policy and Management) from Columbia University, New York.
Prof Andreas Diacon
Topic: The development and evaluation of novel anti-tuberculosis drugs - where to from here?
Prof Andreas Diacon, MD, PhD, is associate professor at Stellenbosch University and consultant for pulmonology at Tygerberg Academic Hospital, Cape Town. As the founder of Task Foundation he is investigating novel anti-tuberculosis agents and treatments that are likely to change tuberculosis treatment. He holds various collaborative research grants.
Prof Bavesh Kana
University of the Witwatersrand and Chair of the 4th South African TB Conference
Topic: Differentially Culturable TB Bacteria: Implications for diagnosis, treatment response and recurrent disease
Professor Bavesh Kana is the head of the University of the Witwatersrand (Wits) node of the DST/NRF Centre of Excellence for Biomedical TB Research, Johannesburg, South Africa, where he studies tuberculosis with a focus on identifying new drug targets and biomarkers to monitor treatment response and risk of disease recurrence. He obtained his PhD at Wits and has worked in several US institutions including the University of Pennsylvania, Texas A&M University, the Public Health Research Institute and Harvard Medical School. Prof. Kana was also appointed as an Early Career Scientist of the Howard Hughes Medical Institute (2012-2016) and was selected as one of the 200 top young South Africans by the Mail and Guardian newspaper. He is also involved in the development of next-generation diagnostic verification reagents for quality assurance and verification of tuberculosis molecular diagnostics. Some of the reagents developed in his laboratory are now being deployed in over 20 countries through a spinoff company started by Wits University.
Prof Gavin Churchyard
The Aurum Institute
Topic: The role of X-Ray in finding new TB cases - old school or new window of opportunity?
Prof Gavin Churchyard is the founder and Group CEO of The Aurum Institute, a not for profit, public benefit organization. He is an Honorary Professor at the University of Witwatersrand and the London School of Hygiene and Tropical Medicine. He is the principal investigator on numerous investigator initiated TB trials conducted in South Africa and other African countries. He has contributed to national and international guidelines for TB and HIV, and has published widely in the areas of TB and HIV treatment and prevention.
Prof Keertan Dheda
University of Cape Town
Topic: Fighting an old enemy: new approaches to TB diagnosis and management.
Keertan Dheda is Professor of Respiratory Medicine, and Head of the Division of Pulmonology at the University of Cape Town. He directs the interventional pulmonology program at UCT, which includes bronchial thermoplasty, ultrasound-guided mediastinal biopsy (EBUS TBNA) and medical thoracoscopy.
His research work focuses on the epidemiology, diagnosis, transmission, and treatment of TB. He has published over 200 peer-reviewed papers including 4 first or senior author original publications in The Lancet. He has been the recipient of several prestigious awards including the International Union Against Tuberculosis and Lung Disease Scientific Award. He has given plenary and keynote addresses at several international conferences. He is the current president of the South African Thoracic Society.
Prof Edward Nardell
Harvard Medical School
Topic: Infection control issues and HCW protection
Professor Edward Nardell is a physician researcher at Harvard Medical School, based at Brigham & Women's Hospital, Boston. For 45 years he has studied airborne TB transmission and how to control it. He and collaborators at the Airborne Infections Research (AIR) Facility, Mpumalanga, have shown that human to guinea pig transmission can result in transient infection, that upper room germicidal UV (GUV) is highly effective in reducing transmission, and that patients using surgical masks is about 56% effective to control the spread of TB. Most effective of all interventions, the group has shown, is effective treatment. This has led to a refocused, intensified approach to institutional TB transmission control called FAST - Find cases Actively, Separate temporarily, and Treat effectively based on molecular DST
Dr Norbert Ndjeka
Director, DR-TB, TB/HIV unit, National TB Control Programme
Topic: Update on DR TB in SA and impact of treatment with Bedaquiline
Dr Norbert Ndjeka, a Specialist Family Physician, is also the Chair of the Regional Green Light Committee (rGLC) - Afro and a Member of the WHO Task Force on introduction of new and repurposed medicines for tuberculosis.
Dr Ndjeka, originally from the DRC, developed his passion for DR TB during his tenure as the Clinical Head of the Limpopo MDR-TB unit, a provincial facility that he helped established. Dr Ndjeka held a joint appointment of Senior Specialist in Family Medicine for Limpopo province and Senior Lecturer in Family Medicine under the University of Limpopo. He also served as MDR-TB and Infection Control Advisor, University Research Corporation.
Dr Neel Gandhi
Topic: Tracing of XDR and MDR TB cases in KZN and studying transmission.
Dr Gandhi, M.D is Associate Professor in the Departments of Epidemiology, Global Health and Infectious Diseases at Emory University’s Rollins School of Public Health and Emory School of Medicine. Dr. Gandhi has been engaged in clinical research in Tuberculosis and HIV co-infection since 1998. Since 2002, Dr Gandhi has led a research team focused on epidemiology and clinical research studies to improve care for TB patients co-infected with HIV, including those with MDR and XDR TB. His research group has demonstrated that transmission of drug-resistant TB strains, in healthcare and community settings, is a major factor in driving the rapid expansion of the epidemic. His group is now investigating the risk of developing resistance to bedaquiline, as well as drug-drug interactions with antiretroviral therapy, among pre-XDR and XDR TB patients.